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KMID : 0615720100270030047
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Jouranl of Korean Acupuncture and Moxibustion society
2010 Volume.27 No. 3 p.47 ~ p.57
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Experimental Study of Taegye(KI3),Taebaek(SP3) Draining Acupuncture on the Improrement of Cerebral Blood Flow and Arterial Blood Pressure
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Chun Hea-Sun
Ryu Chung-Ryul
Cho Myoung-Rae
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Abstract
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Experimental Study of Taegye(KI3) Taebaek(SP3) Draining Acupuncture on the Improvement of Cerebral Blood flow and Arterial Blood Pressure. Objectives : This study was designed to investigate the effects of acupuncture on Taegye(KI3) Taebaek(SP3) draining and determine the mechanism of action of PCBL by measuring the changes of regional cerebral blood flow (rCBF) and mean arterial blood pressure (MABP) in normal rats. Methods : This study was designed to investigate whether acupuncture on Taegye(KI3)?Taebaek(SP3) draining affect Regional cerebral blood flow(rCBF), Mean arterial blood pressure(MABP) in normal rats. To make manifest whether acupuncture on Taegye(KI3)?Taebaek(SP3) draining was mediated by inhibitor of cyclooxygenase or guanylate cyclase which diate arterial diameter. Results 1. Acupuncture on Taegye(KI3)?Taebaek(SP3) draining significantly increased rCBF but decreased MABP. This result suggests that Acupuncturing on Taegye(KI3)?Taebaek(SP3) draining might significantly increase rCBF by dilating arterial diameter. 2. Acupuncture on Taegye(KI3)?Taebaek(SP3) draining induced increase of rCBF was significantly inhibited by pretreatment with indomethacin (1 ㎎/㎏, i.p.), an inhibitor of cyclooxygenase. 3. This result suggests that the action of Acupuncture on Taegye(KI3)?Taebaek(SP3) draining might be mediated by cyclooxygenase.
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KEYWORD
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Taegye(KI3) Taebaek(SP3) Draining Acupuncture, Regional cerebral blood flow, Mean arterial blood pressure
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